• Vertex Pharmaceuticals
  • $120,300.00 -141,170.00/year*
  • Boston , MA
  • Scientific Research
  • Full-Time

Full-Time Job Description: Vertex Pharmaceuticals is currently searching for a talented, highly motivated and creative bench research scientist to join a dynamic research team dedicated to discovering new therapeutic agents for serious renal diseases. Candidates will report directly to the project leader. This position will focus on understanding molecular and cellular mechanisms of disease using advanced cell engineering and cell biological techniques. The applicant should have a strong background in understanding membrane and cell biology and the downstream second messenger signaling pathways. The applicant will be integrated into a fast-paced drug discovery team that includes cell biologists, pharmacologists, biochemists, structural biologists, medicinal chemists and drug metabolism experts. Additional duties and responsibilities include but are not limited to the following: Plan, and direct research efforts of several research projects. Develop and manage relationships with potential academic advisors and research partners. Help to set strategy and be an integral part of research projects from ideation to go/ no go decision points. Key Responsibilities:Independently design and execute key studies to understand disease biology, elucidate mechanism of action at the molecular and cellular level, and support drug discovery projectsPerform advanced/complex experimental troubleshootingCritically analyze and interpret complex data, and effectively document and communicate results to a variety of audiencesContribute effectively to the projects in a multi-disciplinary team environmentApply and master several techniques in Cell Biology (cell/tissue cultures) and Molecular Biology (quantification of gene expression, mutagenesis studies, etc.)Contribute significantly to Microscopy (Immunofluorescence and/or High Content Imaging) and/or Flow cytometry experimentsImplement a strategy to discover novel therapeutic agents in several therapeutic areas to support drug discovery programsProvide strong scientific and technical leadership, utilizing extensive technical expertise in new technology/techniques to support drug discoveryWork effectively with colleagues from cross-functional disciplines (Chemistry, pharmacology, DMPK and toxicology)LI-BS1 Minimum Qualifications: Ph.D./Post Doc in in Cellular, Molecular Biology, Biochemistry or any related field and 5 years of experience in drug discovery in a pharmaceutical/ biotechnology settingOther Requirements:Ability to achieve goals within an allotted timeframe, and deliver high quality results;Strong analytical capabilities and scientific critical judgmentAbility to work in a fast-paced and ever changing environment,Strong communication skills and ability to work cross functionally within teams. Company Information: Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious and life-threatening diseases. We discovered and developed the first medicines to treat the underlying cause of cystic fibrosis (CF), a rare, life-threatening genetic disease. In addition to clinical development programs in CF, Vertex has more than a dozen ongoing research programs focused on the underlying mechanisms of other serious diseases. Founded in 1989 in Cambridge, Massachusetts, our corporate headquarters is now located in Boston's Innovation District, and our international headquarters is in London, United Kingdom. We currently employ approximately 2,500 people in the United States, Europe, Canada, Australia and Latin America with nearly two-thirds of our staff dedicated to research and development. Vertex is consistently recognized as one of the industry?s top places to work by Science Magazine, The Boston Globe, Boston Business Journal and the San Diego Business Journal. Our research and medicines have also received esteemed recognitions, including the Robert J. Beall Therapeutics Development Award, the French Prix Galien and the British Pharmacological Society awards. For additional information and the latest updates from the Company, please visit www.vrtx.com. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistancevrtx.com. Req ID: 12145BR

by Jobble

Associated topics: biomaterials, biomedical, biophysics, bioprocess, fermentation, hereditary, medical, msat, nutrition, pathogenesis

* The salary listed in the header is an estimate based on salary data for similar jobs in the same area. Salary or compensation data found in the job description is accurate.

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