SME, therapeutic monoclonal antibody engineering and development
US - Pennsylvania
The successful candidate will provide strategic and practical guidance to the client in the selection and engineering of therapeutic monoclonal antibodies against infectious disease targets, participate in the selection of a suitable contract research organization (CRO) to execute the development and liaise with the selected CRO on behalf of the client, providing technical guidance.
The client is a virtual company and the majority of the work can be completed remotely; however, the client prefers US East Coast-based consultants to easily allow for scheduling of teleconferences and travel to on site meetings on an as needed basis, including New York, Pennsylvania and Florida, as well as travel to the selected CRO(s).
The individual's support will be part-time typically and the duration of the contract will be at least 1 year.
BS/MS (Ph.D. preferred) in molecular biology, biotechnology, biochemistry or other relevant discipline
Minimum 3 years experience in development and optimization of therapeutic monoclonal antibodies; experience that includes in an industry setting is preferred
Familiarity with upstream process development for monoclonal antibodies preferred
Experience in the following:
therapeutic monoclonal antibody generation, selection, optimization of antigen binding and effector functions, functional screening/ranking assays development
mammalian protein expression, production and purification required
familiarity with phage display or related antibody library selection technique