Associate Scientist (Lexington)

Compensation

: $102,855.00 - $169,240.00 /year *

Employment Type

: Full-Time

Industry

: Scientific Research



Your Role:

We are seeking an Associate Scientist to be a part of the Virus and Gene Therapy Bioprocessing (VGTB) team. The successful candidate will support the development of unit operations for Adeno-associated virus (AAV) and Lentivirus (LV) viral vector production utilizing the MilliporeSigma line of products. This is a customer-facing process development group with expertise required in both upstream and downstream activities associated with viral vector manufacturing. You will also provide input for areas of innovation and new product development to advance MilliporeSigma as the leader in viral vector bioprocessing.

As a member of the VGTB team, your responsibilities include the planning and execution of experimental designs using a DoE based approach, maintenance of adherent and suspension cell line used for gene therapy applications, bench and pilot scale virus production, analytical analysis for product quality/process recoveries, good documentation skills, and general lab maintenance duties. This position requires a combination of intensive laboratory work, generation and delivery of scientific reports, and organization of documents. The candidate will work in a matrix environment as a member of a highly dynamic team, working on multiple projects and contributing to the development of current and future cell-line engineering technologies and methods.

Who You Are:

Minimum Qualifications:

  • Bachelors degree in Biology, Biochemistry, Biomedical Engineering or other scientific or engineering discipline
  • 1+ years experience with aseptic technique
  • 1+ years of mammalian cell culture experience
  • Preferred Qualifications:

  • 2+ years experience in product or process development for bioprocessing
  • 2+ years hands-on experience in Upstream or Downstream Bioprocessing unit operations and development and use of analytical assays
  • 1+ years experience in troubleshooting automated instrumentation and process equipment
  • Proficiency in molecular biology methods
  • Experience with LV and/or AAV viral vector production at pilot scales (up to 50L)
  • Experience designing experiments for and analyzing data from mammalian cell cultures in bioreactors
  • Knowledge and/or experience developing GMP processes
  • Knowledge of downstream unit operations (cell clarification, tangential flow filtration, and various chromatography systems) desired
  • Ability to exercise significant judgment when analyzing complex projects and demonstrate a high level of scientific achievement and understanding
  • Experience with various bioinformatic and office computer software systems.
  • Ability to thrive in a fast-paced team environment and the ability to work efficiently on challenging complex projects with aggressive timelines.
  • Excellent communication and organizational skills
  • RSRMS


    Associated topics: bioengineering, bioinformatics, biology, genome, metabolism, neurobiology, pathophysiology, physical, protein, virus * The salary listed in the header is an estimate based on salary data for similar jobs in the same area. Salary or compensation data found in the job description is accurate.

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