Lygos is an industrial biotechnology company developing novel microbial technologies for the fermentative production of commodity and specialty chemicals. Lygos identifies expensive, environmentally hazardous, and harmful chemical and petrochemical production processes used today and develops safe, renewable routes to the same products. Lygos is seeking to hire a Scientist to support its metabolic engineering needs to develop new microbial strains to efficiently produce a variety of products.
Design, strain construction, strain characterization, protocol development, modelling and exploratory research will be necessary elements of the successful applicant s duties. The successful applicant will be expected to advance critical aspects of Lygos strain engineering program through both effective individual and team efforts. Research objectives are milestone driven (biocatalyst yield, titer, and productivity) and require workflows directed toward achieving these milestones. It is anticipated that this position will require > 75% time in-lab at the bench.
Work in close collaboration with team to conceive, plan, design and successfully complete projects to test new strain engineering hypotheses.
Maintain an in-depth knowledge of yeast cellular physiology and metabolism and advances in synthetic biology and yeast strain engineering.
Prepare technical reports, quantitative analyses, protocols and scientific presentations.
Close collaboration with all aspects of Lygos team, including synthetic biology, analytical chemistry, bioinformatics, and fermentation groups to interpret data and find creative solutions to problems.
Work to develop strain, enzyme, pathway, and process-related intellectual property.
May also be expected to supervise Research Associates.
There will remain significant time and opportunity to also participate in many other aspects of Lygos technical efforts, including: protein engineering, adaptive evolution, high-throughput screening and other areas of technology development. Lygos works closely with all employees to support career development and facilitate the learning of new skill sets.
Education and Experience Requirements
Energetic, hard-working, perseverant and creative team player with a demonstrated ability to plan and execute multiple demanding independent research projects.
A Ph.D. or Masters (with > 2 years of relevant experience post-Masters) with an emphasis on metabolic engineering, synthetic biology or protein engineering.
Proficient with genetic engineering bench work.
Demonstrated success in technical proficiency, scientific creativity, collaborations with others.
Strong organization skills and proven ability to manage details.
Secondary Knowledge and Skill Considerations
Strong verbal and written communication skills.
Ability to deliver on projects and assignments within timeframes and budgets.
Experience engineering a range of microorganisms a plus.
Experience working in a high-throughput environment preferred.
Effective problem solver that is willing to work flexibly and take on diverse responsibilities within a fast-paced, multitasking start-up company environment.
Lygos offers a competitive total compensation packages including an employee incentive stock option plan. Benefits include medical, dental, vision, 401(k) plan, paid holidays and vacation time.